Pandosia was an ancient Greek city of Epirus. Together with the other Elean colonies Bucheta and Elatea it was a city of the Cassopaeans, who were a sub-tribe of the Thesprotians. It was located south of the river Acheron.
Very little is known about its history, save that Pandosia and its neighbours Bucheta and Elatea were conquered by Philip of Macedon. He transferred the cities to the possession ofAlexander I of Epirus.
Alexander was allegedly warned by an oracle to beware of Pandosia and the Acheron river. When he left Epirus for a military campaign on the Italian Peninsula he thought himself to be safe, far away from the two places. He did not realize there was also a city called Pandosia and identically named river in Bruttium until it was too late. He was killed there during the Battle of Pandosia.